Norbert Haider

Ao. Univ.-Prof., Dr. rer. nat., Mag. pharm.

Address: Department of Drug and Natural Product Synthesis, Faculty of Life Sciences, University of Vienna, Althanstraße 14, A-1090 Vienna, Austria
Tel.: +43-1-4277-55624
Fax: +43-1-4277-9556
e-mail: norbert.haider@univie.ac.at (no spam, no viruses, no HTML mails, please)

Research:

Medicinal Heterocyclic Chemistry:
- Synthesis, reactivity, and biological activity of pyridazines and fused pyridazines
- Synthesis of higher-annelated heterocyclic systems (e.g. fused carbazoles and indoles; new ellipticine and olivacine analogs as potential antitumor agents)
Inverse-electron-demand Diels-Alder reactions. Here is an example.

For more detailed information, there are lists of publications and conference contributions as well as electronic reprints of some recent papers:
N. Haider, K. Mereiter, and R. Wanko, Heterocycles, 38, 1845 (1994) (PDF, 95k)
N. Haider and R. Wanko, Heterocycles, 38, 1805 (1994) (PDF, 30k)
N. Haider, Acta Chimica Slovenica, 41, 205 (1994) (PDF, 67k; review)
N. Haider, K. Mereiter, and R. Wanko, Heterocycles, 41, 1445 (1995) (PDF, 130k)
N. Haider, Heterocycles, 41, 2519 (1995) (PDF, 37k)
G. Fülep and N. Haider, Molecules, 3, 10 (1998) (PDF, 153k)
N. Haider, E. Mavrokordatou, and A. Steinwender, Synth. Comm., 29, 1577 (1999) (PDF, 32k)
N. Haider, J. Käferböck and P. Mátyus, Heterocycles, 51, 2703 (1999) (PDF, 107k)
N. Haider and J. Käferböck, Heterocycles, 53, 2527 (2000) (PDF, 77k)
E. Abdel-Rehem and N. Haider, ARKIVOC, 2, 21 (2001) (PDF, 99k)
E. Fidesser, N. Haider, and R. Jbara, ARKIVOC, 2, 133 (2001)
N. Haider and E. Sotelo, Chem. Pharm. Bull., 50, 1479 (2002) (PDF, 161k)
N. Haider, T. Kabicher, J. Käferböck, and A. Plenk, Molecules, 12, 1900 (2007) (PDF, 76k).
N. Haider, I. Hochholdinger, P. Mátyus, and A. Wobus, Chem. Pharm. Bull., 58, 964 (2010) (PDF, 255K)

More information about recent research projects can be obtained from these electronic posters:

Synthesis of Heterocycle-Annelated Naphthyridones with a Bridgehead Nitrogen Atom
(presented at the 1st Electronic Conference on Heterocyclic Chemistry (ECHET96).

Diels-Alder Reaction of Pyrano[3,4-b]indolones with Electron-Poor Pyridazinones: a New Pathway to Carbazole-Fused Pyridazines
(presented at the 2nd Electronic Conference on Heterocyclic Chemistry (ECHET98).

ChemInformatics:

Development of chemical database tools:

Creating a web-based, searchable molecular structure database using free software
Seminar lecture: How to create a web-based molecular structure database with free software
checkmol/matchmol, a multi-purpose command-line utility, e.g. for 2D structure/substructure matching
mol2ps, a utility program for 2D depiction of molecular structures (Postscript)
MolDB5R, a fully functional package of PHP and Perl scripts for running a molecular structure database; for a recent publication, see:
Haider, N., Functionality Pattern Matching as an Efficient Complementary Structure/Reaction Search Tool: an Open-Source Approach. Molecules, 15, 5079-5092 (2010).

Development of utilities for spectroscopic data processing

JDXview, a JCAMP-DX spectrum viewer
jdx2jdx, a command-line JCAMP-DX data transcoder
IRview, a viewer for infrared spectra (Perkin-Elmer and JCAMP-DX format)
MSview, a viewer for mass spectra in Wi(e)n-MS format

Development of novel web services based on Robien's CSEARCH/NMRpredict spectral database and prediction system (in collaboration with Wolfgang Robien, Institute of Organic Chemistry, University of Vienna).

Teaching:

Trenn- und Analysenmethoden organischer Arzneistoffe (VO)
Computeranwendungen in der Pharmazeutischen Chemie (SE)
Arzneistoffsynthese (PR)
Pharmazeutisch-Chemisches Praktikum für Fortgeschrittene
Aktuelle Forschungsergebnisse in der pharmazeutischen Chemie
supervision of diploma (Master) and PhD theses

Other Activities:

Co-founder of the PharmXplorer project, a multi-functional, all-Austrian e-Learning platform for pharmacy students, graduates, and lecturers
e-Learning coordinator of the Faculty of Life Sciences
IT coordinator of the Faculty of Life Sciences
Coordinator of a joint e-Learning deployment project involving all pharmaceutical departments at the University of Vienna (see project homepage)
System administrator of various local computer systems
Webmaster, postmaster, local IT manager
Organiser and chairman of the EUFEPS session "Pharmaceutical Sciences in-silico learning systems: value and availability" at the Pharmaceutical Sciences World Congress 2007 (Amsterdam, NL).
Organiser of the 1^st European Workshop on Computer-Aided Learning in the Pharmaceutical Sciences and of the 2^nd European Workshop on Computer-Aided Learning in the Pharmaceutical Sciences
Head of the EUFEPS Branch Office for in-silico Systems and Learning
Local project leader of the IMI-JU project PharmaTrain

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N. Haider, 2002-11-04; last update: 2011-01-13